HCP Connect Clinical Author
Dr. Vikram Patel
Neurology
Specialty
Neurology
Clinical Updates
29
Experience
12 Years
Author Biography
About Dr. Vikram Patel
Dr. Vikram Patel is a senior neurologist with 12 years of clinical experience across stroke, epilepsy, and movement disorders. He completed his DM in Neurology following an MD in General Medicine and has a long-standing interest in acute stroke care and neuro-imaging. He has mentored residents and led several teaching programmes. He writes to bridge emerging neuroscience and everyday bedside practice.
Published Work
Recent Clinical Updates
29 articles
Neurology
FDA Approves Efgartigimod for gMG: 67.7% MG-ADL Response
Efgartigimod (VYVGART HYTRULO) FDA approval for generalized myasthenia gravis: 67.7% MGâADL responder rate in Study 1; subcutaneous weekly Ă4 dosing [11].
Neurology
lecanemab and donanemab: amyloid confirmation and PET criteria for patient selection
Leqembi and Kisunla labels require amyloid confirmation before treatment; donanemab cites amyloid PET stopping thresholds; MRI schedules and dosing are summarized.
Neurology
FDA Approves ofatumumab for Relapsing MS: Cuts Relapse Rate 51%
ofatumumab relapsing multiple sclerosis FDA approval: ARR reduced to 0.11 vs 0.22 (51% RR) and 3âmonth disability progression 10.9% vs 15.0% in trials.
Neurology
FDA Approves Copper Histidinate for Menkes: Cuts Death Risk 78%
FDA approves copper histidinate (ZYCUBO) for pediatric Menkes disease; early treatment cut death risk 78% (HR 0.22; 95% CI 0.10-0.49) [12].
Neurology
FDA Approves Atogepant for Episodic Migraine: 1.7âDay MMD Drop (ADVANCE)
Atogepant (Qulipta) approved for episodic migraine; ADVANCE showed 1.7âday reduction in monthly migraine days with 60 mg vs placebo. atogepant episodic migraine
Neurology
TEMPO-3: Tavapadon Increases GoodâOnâTime 1.10 Hours in PD
Tavapadon TEMPO-3 trial: increased good-on-time by 1.10 hours in Parkinson disease; reduced off-time by 0.94 hours. Safety: nausea 14.3%, dyskinesia 10.0% [1].
Neurology
FDA Approves efgartigimod alfa for gMG: 67.7% MGâADL Response
FDA approves efgartigimod alfa (VYVGART HYTRULO) for generalized myasthenia gravis; 67.7% MGâADL response in Study 1 supports SC formulation.
Neurology
FDA Approves erenumab for Migraine: 43.3% â„50% MMD Responders
erenumab migraine prevention: FDA label shows AIMOVIG 70 mg reduced monthly migraine days (â3.2) and produced 43.3% â„50% responder rate versus 26.6% placebo.
Neurology
Tolebrutinib Reduced Progression Risk (HR 0.69) in Nonrelapsing SPMS
Tolebrutinib reduced progression risk (HR 0.69) in nonrelapsing secondary progressive multiple sclerosis in the HERCULES trial; trial N=1,131; dose 60 mg daily.
Neurology
Lecanemab: FDA Approves for Alzheimer; CDRâSB Decline 0.45
Lecanemab FDA approval for Alzheimerâs: CLARITY AD showed a -0.45 difference in CDRâSB at 18 months with amyloid PET reduction; label recommends 10 mg/kg IV q2w and MRI ARIA monito...
Gene Therapy
CRISPR Gene Therapy: A New Frontier in Sickle Cell Disease Treatment
Explore the latest advances in CRISPR gene therapy for sickle cell disease and its potential for curative treatment.
Neurology
Improve Parkinson's Symptoms with Targeted Therapy
Discover how optimized speech and movement therapy can improve motor and nonmotor symptoms in Parkinson's disease patients, enhancing overall quality of life.
Medical Devices
Streamline Molecular Testing with Integrated Solutions
Discover how a strategic partnership can simplify workflow and improve biospecimen storage for Contract Research Organizations and pharmaceutical partners.
Neurology
Identify Macromastia to Reduce Headache Risk
Learn how recognizing macromastia in women can help reduce headache risk and improve patient outcomes with referral options and conservative treatments.
Neurology
New Target to Reduce MS Inflammation
Discover how mesenchymal stem cells in secondary progressive multiple sclerosis drive proinflammatory T-cell activity and potential therapeutic targets to reduce inflammation in MS...
Medical Research
Reduce PPIX Accumulation by 30% with GlyT1 Inhibition
Discover how blocking extracellular glycine uptake mitigates protoporphyria, reducing protoporphyrin IX accumulation in erythrocytes and plasma tissues by inhibiting GlyT1.
Medical Research
Boost Transplant Success with Novel Immunosuppression
Discover how costimulation blockade promotes tolerance, reducing rejection in cardiac transplantation and improving patient outcomes with alternative therapies.
Medical Research
New Compound Induces Lytic Cell Death in Tumor Models
Discover how a novel compound triggers pyroptosis, offering a potential therapeutic approach to overcome melanoma's resistance to apoptosis and activate antitumoral immunity.
Medical Research
TBX3 Mutations Linked to Hepatic Clonal Expansion
Discover how somatic mutations in TBX3 impact liver disease, including hepatic clonal expansion and VLDL secretion, with implications for clinical practice.
Health News
Mental Health Screenings in Schools: What's at Stake for Patients
Experts weigh in on proposed changes to mental health screenings in schools, citing potential consequences for early intervention and treatment outcomes.
Medical Research
Long COVID's Impact on Menstrual Cycles
Research explores the bidirectional relationship between long COVID and menstruation, shedding light on menstrual disturbances in women with long-term COVID-19 symptoms.
Medical Research
Identify Aggressive Breast Cancer Sooner
New lymph node study reveals how breast cancer evades immune detection, informing treatment choices and survival chances for patients.
Neurology
New Treatment Lowers Heart Attack and Stroke Risk
Learn about a new medication that can help reduce the risk of heart attack, stroke, and cardiovascular death in people with type 2 diabetes.
Medical Research
Unlock Tomatillo Benefits
Discover the taste and health benefits of tomatillos, a nutrient-rich food that's easy to add to your diet for a healthier you.
Wellness
Identify Hidden Heart Attack Signs
Learn to distinguish between heartburn and potential heart attack symptoms to improve patient outcomes and save lives.
Neurology
Empower Your Neurology Career
Learn how to overcome challenges and advance your neurology career with expert-led sessions and networking opportunities at the Women in Neurology Conference.
Neurology
Empower Your Neurology Career with Community Support
Connect with fellow women neurologists, enhance your skills, and relax at a weekend conference designed for professional and personal growth.
Neurology
Reduce Dyskinesia with Continuous Infusion Therapy
Discover how continuous infusion therapies can provide stable symptom control and reduce "off" time for Parkinson's disease patients experiencing motor fluctuations.
Digital Health
AI Automates 30% of Patient Calls
Discover how conversational AI can reduce administrative burdens and improve patient experience, freeing up more time for healthcare professionals to focus on care.