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Recent Clinical Updates
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SP

HCP Connect Clinical Author

Dr. Shruti Pandey

Hematology

Credentials: MBBS, MD (General Medicine), DM (Clinical Haematology)

Specialty

Hematology

Clinical Updates

18

Experience

6 Years

Author Biography

About Dr. Shruti Pandey

Dr. Shruti Pandey is a clinical haematologist with 6 years of experience. She completed a DM in Clinical Haematology following an MD in General Medicine, focusing on leukaemias and coagulation disorders. She takes keen interest in the evolving role of targeted and cellular therapies. Her writing translates haematology advances into practical clinical guidance.

Published Work

Recent Clinical Updates

18 articles

Hematology

CAR-T Therapy in DLBCL and Multiple Myeloma: Outcomes and Optimization

ciltacabtagene autoleucel multiple myeloma: deep-dive on CARTITUDE-4, real-world comparisons, and CAR-T optimization for hematologists.

Aug 18, 2026|9 min read|Via PubMed

Hematology

FDA Approves Acalabrutinib + Venetoclax for CLL/SLL: PFS HR 0.65 in AMPLIFY

acalabrutinib chronic lymphocytic leukemia: FDA approves acalabrutinib plus venetoclax for adults with previously untreated CLL/SLL (AMPLIFY PFS HR 0.65).

Aug 17, 2026|5 min read|Via FDA

Hematology

AURORA: Bitopertin Reduced Protoporphyrin‑IX 49.8% in Erythropoietic Protoporphyria

Bitopertin erythropoietic protoporphyria: AURORA trial showed -49.8% protoporphyrin‑IX change with 60 mg vs placebo; reduced phototoxic reactions and favorable tolerability.

Jul 22, 2026|5 min read|Via PubMed

Hematology

narsoplimab: FDA Approves for TA-TMA; 61% TMA Response

narsoplimab TA-TMA: FDA approves Yartemlea for hematopoietic stem cell transplant-associated thrombotic microangiopathy with 61% TMA response.

Jul 19, 2026|5 min read|Via FDA

Hematology

FDA Approves Daratumumab for NDMM Ineligible for ASCT: 52.3% MRD

FDA approves daratumumab (DARZALEX FASPRO) with VRd for newly diagnosed multiple myeloma in ASCT-ineligible adults; CEPHEUS: 52.3% MRD vs 34.8%, PFS HR 0.60.

Jul 14, 2026|6 min read|Via DailyMed

Hematology

FDA Approves Fitusiran for Hemophilia A/B: Median Treated ABR 3.7

Fitusiran (QFITLIA) approved for hemophilia A/B prophylaxis; median treated ABR 3.7 in ATLAS-OLE; antithrombin-guided dosing and safety monitoring required.

Jul 11, 2026|7 min read|Via PubMed

Hematology

FDA Approves imetelstat for LR-MDS: 40% 8-week RBC-TI in IMerge

Imetelstat (RYTELO) FDA approved for transfusion-dependent low‑ to intermediate‑1 risk MDS after IMerge showed 40% achieved 8‑week RBC‑TI vs 15% with placebo.

Jul 10, 2026|5 min read|Via PubMed

Medical Research

Novel Therapy Achieves 90% Response in Rare Sarcoma

New targeted radiation approach reduces cancer activity and provides symptom relief in patients with solitary fibrous tumors, a rare and often malignant soft tissue tumor.

Apr 24, 2026|2 min read|Via Medical Xpress

Medical Research

Cut Opioid Relapse Rates with Evidence-Based Meds

Learn how primary care clinics can help curb the opioid epidemic with effective medications and overcome treatment barriers to improve patient outcomes.

Apr 20, 2026|2 min read|Via Medical Xpress

Healthcare Business

Integrated Care Cuts Pediatric Behavioral Issues by 30%

Discover how integrated primary care services can improve pediatric behavioral health outcomes and reduce symptom scores in children, enhancing overall well-being and quality of li...

Apr 18, 2026|5 min read|Via American Journal Managed Care

Medical Research

Identify Microcephaly Cause with SNW1 Gene Mutation

Discover how mutations in the SNW1 gene are linked to neurodevelopment disorders with microcephaly, informing diagnosis and treatment approaches for affected patients.

Apr 13, 2026|64 min read|Via Journal of Clinical Investigation

Medical Research

Uncover Root Causes of Liver Fibrosis

Discover how metabolic dysfunction and lipid accumulation contribute to liver fibrosis, and learn how to identify and manage underlying causes in your patients.

Apr 13, 2026|17 min read|Via Journal of Clinical Investigation

Medical Research

Uncover Microbiome's Role in RA Progression

Discover how microbiome changes impact rheumatoid arthritis treatment and patient outcomes, and what it means for your practice.

Apr 12, 2026|25 min read|Via Journal of Clinical Investigation

Medical Research

Reduces EPP-Related Liver Disease by Targeting Erythroid PPIX

Discover how inhibiting GLYT1 mitigates liver disease in erythroid protoporphyria, reducing phototoxicity and improving patient outcomes.

Apr 11, 2026|31 min read|Via Journal of Clinical Investigation

Medical Research

New Opioid 20x Stronger Than Fentanyl Fuels Overdose Crisis

A highly potent synthetic opioid is driving the overdose crisis, with potency hundreds of times stronger than morphine, posing a new threat to patient safety.

Apr 7, 2026|3 min read|Via Medical Xpress

Pharmaceutical

Novel Protein Degraders May Revolutionize Immune Condition Treatment

Discover how new protein degrader drugs can improve treatment outcomes for immune conditions, with potential for enhanced efficacy and reduced side effects.

Mar 28, 2026|2 min read|Via BioPharma Dive

Digital Health

Boost Trial Efficiency with Data-Driven Site Selection

Discover how AI-powered site selection can streamline clinical trials, saving time and resources for sponsors and improving trial accessibility.

Mar 28, 2026|3 min read|Via HIT Consultant

Health IT

Identify K 18 Small White Pill for Patient Safety

Quickly identify the K 18 small white pill to ensure patient safety and accurate medication administration in your practice.

Mar 24, 2026|12 min read|Via HIStalk