The Weekly Roundup for November 7, 2025: Recent Publications in Women’s Mental Health

PMS AND PMDD

No articles this week

INFERTILITY AND MENTAL HEALTH

No articles this week

PSYCHIATRIC ILLNESS DURING PREGNANCY

Association between hyperemesis gravidarum and depression: a national register-based controlled study in Finland. Terävä-Utti E, Nurmi M, Laitinen L, Rissanen T, Järvenpää T, Polo-Kantola P. Lancet Psychiatry. 2025 Nov;12(11):841-851.

Women with hyperemesis gravidarum were more likely to have pre-pregnancy and new onset depression compared to controls, with earlier onset after delivery and persistent risk for years postpartum.

History of Concussion and Risk of Severe Maternal Mental Illness: A Population-Based Cohort Study. Krueger S, Vigod SN, Chan V, Mollayeva T, Alonzo R, Chung H, Brown HK. J Clin Psychiatry. 2024 Nov 4;85(4):24m15373.

Birthing people with a history of concussion had increased risk of severe maternal mental illness, especially those without prior mental illness.

Mental Health Assessments for Fetal Interventions. Vangala S, Williams R Jr, Buskmiller CM, Munoz JL. J Clin Psychiatry. 2024 Jun 24;85(3):24l15275.

Psychiatric and psychosocial evaluations are recommended before intrauterine fetal interventions to optimize both surgical and mental health outcomes.

MEDICATIONS AND PREGNANCY

Safety of Valproic Acid Use in Pregnant Women: A Systematic Review and Meta-Analysis. Meta-analysis reveals significantly increased risks with prenatal valproate exposure for neural tube defects, congenital heart defects, cleft lip/palate, genitourinary, and musculoskeletal anomalies compared with other AEDs.

Changes in S-Citalopram Plasma Concentrations Across Pregnancy and Postpartum. Stika CS, Avram MJ, George AL Jr, et al. Clin Pharmacol Ther. 2025 Jul;118(1):106-117.

Intermediate or poor CYP2C19 metabolizers may require dose adjustment for escitalopram in pregnancy, as concentrations may become subtherapeutic.

POSTPARTUM PSYCHIATRIC ILLNESS

Randomized controlled trial investigating the effect of a childbirth and parenting booklet intervention on paternal postpartum depression risk. Ichinose Y, Urayama KY, Okamura M, Sugiura N, Suto M, Sasaki H, Takehara K. BMC Pregnancy Childbirth. 2025 Oct 15;25(1):1095.

A childbirth/parenting booklet alone may not reduce paternal PPD risk; more interactive or tailored interventions may be needed.

A randomized controlled trial investigating the impact of coping strategies training for fathers during pregnancy on postnatal depression among couples. Mozaffari R, Bahrami N, Bahramkhani M, Griffiths MD, Alimoradi Z. J Psychosom Obstet Gynaecol. 2025 Dec 31;46(1):2566074.

Training fathers during pregnancy in coping strategies reduced postnatal depression scores in both mothers and fathers.

A Group Parenting Intervention for Male Postpartum Depression: A Cluster Randomized Clinical Trial. Husain MI, Kiran T, Sattar R, Khoso AB, Wan MW, Singla DR, Umer M, Mangrio R, Bassett P, Chaudhry IB, Zafar SN, Jafri FA, Chaudhry N, Husain N. JAMA Psychiatry. 2025 Jan 1;82(1):22-30.

Group parenting interventions for fathers can significantly decrease postpartum depression symptoms in men and their partners.

MEDICATIONS AND BREASTFEEDING

Psychotropic Medication Exposure via Breast Milk: A Population-Based Descriptive Study in Denmark. Among 446,573 Danish infants exclusively breastfed, 17.6 per 1000 were exposed to at least one psychotropic medication via breast milk.

PERINATAL SUBSTANCE USE

Buprenorphine treatment during the extended postpartum period: a survey of patient experiences. Galati B, Jacobsen H, Kraus M, Mills M, Vaughn B, Williams S, Wenzinger M, Rogers C, Raghuraman N, Kelly J. J Matern Fetal Neonatal Med. 2025 Dec;38(1):2578576.

Patients reported high treatment satisfaction with buprenorphine during the extended postpartum period, but most had a goal of discontinuation; social support for long-term treatment was limited.

Cost-Effectiveness of Treatment for Opioid Use Disorder in Pregnancy and Its Impact on Birth Outcomes. Both methadone and buprenorphine were viable for OUD management in pregnancy, but buprenorphine offered greater lifetime benefits for infant outcomes.

Prevalence of Substance Use Disorders Among Pregnant and Postpartum Women in the United States: A Cross-Sectional Analysis of the National Hospital Care Survey 2020. Rizvi A, Yadav G, Shayeb M, Jain S. Prim Care Companion CNS Disord. 2025 Mar 6;27(2):24br03838.

Nicotine dependence was the most common substance disorder among pregnant/postpartum women in the ED (6.6%), followed by cannabis (1.8%) and opioid (0.6%).

MATERNAL MENTAL HEALTH AND CHILD OUTCOMES

Maternal Psychological Distress Before and After Childbirth and Neurodevelopmental Delay in Toddlers. Matsumura K, Tanaka T, Kuroda M, Tsuchida A, Hatakeyama T, Kasamatsu H, Inadera H; Japan Environment and Children’s Study Group. JAMA Netw Open. 2025 Oct 1;8(10):e2540907.

Maternal psychological distress at one year postpartum, more than distress in pregnancy, was associated with neurodevelopmental delay in toddlers.

Postnatal vs Prenatal Maternal Stress and Offspring Neurodevelopment. Barzilay R. JAMA Netw Open. 2025 Oct 1;8(10):e2540917.

Study commentary highlights that postnatal maternal stress has particular relevance for child neurodevelopmental outcomes.

MENOPAUSE AND MENTAL HEALTH

No articles this week

OTHER TOPICS IN WOMEN’S MENTAL HEALTH